Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 12/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533666 | 0.86 | NR3C1 (0.54) | NR3C1NR3C2PGR | |
| SCHEMBL3529504 | 0.83 | NR3C1 (0.46) | NR3C1NR3C2PGRCYP19A1 | |
| SCHEMBL3530014 | 0.79 | ALDH1A1 (0.45) | NR3C1NR3C2PGR | |
| SCHEMBL18929952 | 0.77 | TRPV4 (0.46) | NR3C1NR3C2PGRCYP19A1 | |
| SCHEMBL5521708 | 0.76 | NR3C1 (0.72) | NR3C1NR3C2PGR | |
| SCHEMBL3954499 | 0.75 | NR3C2 (0.68) | NR3C1NR3C2PGR | |
| SCHEMBL5781333 | 0.75 | NR3C1 (0.63) | NR3C1NR3C2PGR | |
| SCHEMBL14073623 | 0.74 | NR3C1 (0.51) | NR3C1NR3C2PGR | |
| SCHEMBL803017 | 0.72 | TRPV4 (0.56) | CYP19A1 | |
| SCHEMBL3532217 | 0.72 | NR3C1 (0.54) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100581543-C | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | SCHERING AG | 2010-01-20 | — | — | CN | disclosed |