Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018403 | 0.84 | ALDH1A1 (0.43) | CTSSCTSKPSENENALDH1A1HTT | |
| SCHEMBL5988691 | 0.84 | ALDH1A1 (0.43) | CTSSCTSKPSENENALDH1A1HTT | |
| SCHEMBL3265293 | 0.84 | ALDH1A1 (0.43) | CTSSCTSKPSENENALDH1A1HTT | |
| SCHEMBL13223902 | 0.80 | CTSS (0.46) | CTSSCTSKPSENENALDH1A1CA2 | |
| SCHEMBL19318524 | 0.80 | CTSS (0.46) | CTSSCTSKPSENENALDH1A1CA2 | |
| SCHEMBL12672832 | 0.75 | ALDH1A1 (0.41) | CTSSCTSKPSENENALDH1A1HTT | |
| SCHEMBL18931312 | 0.75 | ALDH1A1 (0.41) | CTSSCTSKPSENENALDH1A1HTT | |
| SCHEMBL16440334 | 0.73 | ALDH1A1 (0.42) | CTSSCTSKPSENENALDH1A1HTT | |
| SCHEMBL18870810 | 0.73 | ALDH1A1 (0.42) | CTSSCTSKPSENENALDH1A1HTT | |
| SCHEMBL204043 | 0.71 | ALDH1A1 (0.61) | CTSSCTSKALDH1A1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10039754-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2018-08-07 | — | — | US | disclosed |
| US-20170157104-A1 | Anti-Viral Compounds | ABBVIE INC. (US) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170157104-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | CTSS 445/4885CTSK 632/4885PSENEN 4172/4885 |
| US-10039754-B2 | Anti-viral compounds | HAVCR2, EIF2AK2, MAVS | CTSS 445/4885CTSK 632/4885PSENEN 4172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.