Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18232451 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL5429971 | 0.79 | ALDH1A1 (0.51) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL10912929 | 0.79 | LOXL2 (0.44) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL7360165 | 0.78 | LOXL2 (0.54) | ALDH1A1KDM4EGLASMN1; SMN2NPC1 | |
| SCHEMBL13102158 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4911691 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL22456025 | 0.73 | SIGMAR1 (0.49) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL2185893 | 0.73 | SIGMAR1 (0.68) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL2567878 | 0.72 | SLC2A4 (0.41) | ALDH1A1LMNA | |
| SCHEMBL13018522 | 0.72 | HRH1 (0.47) | ALDH1A1LMNAHTTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017096315-A1 | TRIAZOLE DAGL(α) INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-06-08 | — | — | WO | disclosed |