Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19571047 | 0.81 | PDE2A (0.41) | — | |
| SCHEMBL14736533 | 0.81 | CA2 (0.33) | CA2CA4 | |
| SCHEMBL9929298 | 0.80 | PDE2A (0.33) | CA2CA4 | |
| SCHEMBL9928957 | 0.80 | LMNA (0.37) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL9929353 | 0.78 | LMNA (0.36) | CA2CA4 | |
| SCHEMBL21517191 | 0.77 | CA2 (0.31) | CA2CA4 | |
| SCHEMBL9928990 | 0.73 | NCOA1 (0.32) | CA2CA4 | |
| SCHEMBL20816035 | 0.72 | HSD17B10 (0.35) | — | |
| SCHEMBL9952471 | 0.72 | HSD17B10 (0.35) | — | |
| SCHEMBL9952276 | 0.71 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158696-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | INCYTE CORPORATION | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158696-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | PIK3CA, PIK3CD, PI4KB | CA2 4854/4885CA4 4865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.