SCHEMBL18935944

SCHEMBL18935944

O=C(O)C1=NOC(CCCOCCc2ccccc2)C1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
LMNA P02545 1/20 0.44
ITGB3 P05106 4/20 0.40
ITGAV P06756 3/20 0.40
ITGA2B P08514 2/20 0.40
PPARG P37231 2/20 0.39
PPARA Q07869 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19194259 0.91 MEN1 (0.43) MEN1KMT2AHDAC3HDAC1HDAC2
SCHEMBL17490749 0.89 HDAC3 (0.45) MEN1KMT2AHDAC3HDAC1HDAC2
SCHEMBL18936001 0.87 ALDH1A1 (0.50) MEN1KMT2AHDAC3HDAC1HDAC2
SCHEMBL17490892 0.86 LMNA (0.46) MEN1KMT2AHDAC3HDAC1HDAC2
SCHEMBL17490911 0.85 HDAC3 (0.47) HDAC3HDAC1HDAC2HDAC10HDAC6
SCHEMBL18936085 0.84 HDAC3 (0.46) HDAC3HDAC1HDAC2HDAC10HDAC6
SCHEMBL17490914 0.84 HDAC3 (0.46) HDAC3HDAC1HDAC2HDAC10HDAC6
SCHEMBL6448155 0.84 LMNA (0.51) HDAC3HDAC1HDAC2HDAC10HDAC6
SCHEMBL18936006 0.82 HDAC3 (0.47) HDAC3HDAC1HDAC2HDAC10HDAC6
SCHEMBL17490859 0.81 LMNA (0.46) MEN1KMT2AHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178323-B1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-06-23 EP disclosed
US-9854803-B2 Noxious arthropod control agent containing amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 US disclosed
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 US disclosed
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 US disclosed
EP-3178323-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2017-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND TRPA1, OPRM1, OPRL1 MEN1 4523/4885KMT2A 2216/4885HDAC3 791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.