SCHEMBL18935982

SCHEMBL18935982

C=CCCCOCc1ccc2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 2/20 0.44
UGCG Q16739 2/20 0.44
GBA2 Q9HCG7 2/20 0.44
RAB9A P51151 1/20 0.43
REN P00797 9/20 0.43
SLC6A2 P23975 3/20 0.42
SLC6A4 P31645 3/20 0.42
SLC6A3 Q01959 3/20 0.42
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
HTR7 P34969 1/20 0.42
HTR2B P41595 1/20 0.42
HTR3A P46098 1/20 0.42
HTR4 Q13639 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
KCNH2 Q12809 2/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28443474 0.94 GBA1 (0.47) GBA1UGCGGBA2RAB9AREN
SCHEMBL7624591 0.83 GBA1 (0.47) GBA1UGCGGBA2RAB9AREN
SCHEMBL7622461 0.82 GBA1 (0.49) GBA1UGCGGBA2RAB9AREN
SCHEMBL7622737 0.81 GBA1 (0.51) GBA1UGCGGBA2RAB9AREN
SCHEMBL18936038 0.80 RAB9A (0.47) RAB9ASLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL7627282 0.80 CYP1A2 (0.48) GBA1UGCGGBA2RAB9AREN
SCHEMBL3269931 0.80 TSHR (0.52)
SCHEMBL13464380 0.79 CYP1A2 (0.53) GBA1UGCGGBA2RAB9AREN
SCHEMBL29217266 0.78 SIGMAR1 (0.54) SLC6A4CYP1A2CYP2A6
SCHEMBL19210354 0.78 TDP1 (0.55) GBA1UGCGGBA2RENCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178323-B1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-06-23 EP disclosed
US-9854803-B2 Noxious arthropod control agent containing amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 US disclosed
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 US disclosed
EP-3178323-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2017-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND TRPA1, OPRM1, OPRL1 GBA1 2925/4885UGCG 3782/4885GBA2 2285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.