Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.30 |
| ▸ | RORB | Q92753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30448114 | 0.82 | P2RX7 (0.38) | P2RX7EPAS1GLAPOLBGAA | |
| SCHEMBL18980143 | 0.80 | GLA (0.37) | GLAPOLBGAATSHRKIF11 | |
| SCHEMBL374673 | 0.78 | IDO1 (0.39) | P2RX7EPAS1GLAPOLBGAA | |
| SCHEMBL28083061 | 0.78 | GLA (0.35) | GLAPOLBGAATSHRKIF11 | |
| SCHEMBL16593769 | 0.77 | P2RX7 (0.35) | P2RX7EPAS1GLAPOLBGAA | |
| SCHEMBL437464 | 0.77 | KIF11 (0.37) | GLAPOLBGAATSHRKIF11 | |
| SCHEMBL27895332 | 0.77 | KIF11 (0.41) | P2RX7EPAS1GLAPOLBGAA | |
| SCHEMBL23674368 | 0.75 | NOTUM (0.35) | GLAPOLBGAATSHRKIF11 | |
| SCHEMBL669761 | 0.75 | P2RX7 (0.42) | P2RX7EPAS1NOTUMENPP3ENPP1 | |
| SCHEMBL669762 | 0.75 | P2RX7 (0.42) | P2RX7EPAS1NOTUMENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298081-A1 | CONDENSED HETEROCYCLIC COMPOUND | KASUMA PARTNERS INC. (JP) | 2017-10-19 | — | — | US | disclosed |
| US-20170298081-A1 | CONDENSED HETEROCYCLIC COMPOUND | KASUMA PARTNERS INC. (JP) | 2017-10-19 | — | — | US | disclosed |
| EP-3178810-A1 | CONDENSED HETEROCYCLIC COMPOUND | Kasuma Partners Inc. (JP) | 2017-06-14 | — | — | EP | disclosed |
| CN-102311401-A | CETP INHIBITORS | MERCK & CO INC | 2012-01-11 | — | — | CN | disclosed |
| CN-102304096-A | CETP inhibitors | MERCK SHARP & DOHME | 2012-01-04 | — | — | CN | disclosed |
| CN-1980904-A | CETP inhibitors | MERCK & CO INC (US) | 2007-06-13 | — | — | CN | disclosed |
| CN-1027341-C | N-Phenylpyrazole Derivative Insecticides | MAY & BAKER LTD (FR) | 1995-01-11 | — | — | CN | disclosed |
| CN-88103601-A | N-PHENYLPYRAZOLE DERIVATIVES | — | 1988-12-28 | — | — | CN | disclosed |
| CN-86106734-A | ARYL PYRIDONES | — | 1987-04-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298081-A1 | CONDENSED HETEROCYCLIC COMPOUND | APOB, NPC1, NPC1L1 | P2RX7 4779/4885EPAS1 2809/4885GLA 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.