Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25C | P30307 | 1/20 | 0.33 |
| ▸ | HPD | P32754 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9117924 | 0.86 | BRD4 (0.33) | BRD4LMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL9395968 | 0.79 | BRD4 (0.44) | BRD4LMNA | |
| SCHEMBL24616656 | 0.78 | LMNA (0.33) | LMNAMCOLN3ALDH1A1POLBL3MBTL1 | |
| SCHEMBL16503638 | 0.77 | ADORA2B (0.34) | ADORA2B | |
| SCHEMBL19235507 | 0.71 | BRD4 (0.36) | BRD4LMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL14491564 | 0.71 | BRD4 (0.36) | BRD4LMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL11716480 | 0.71 | BRD4 (0.34) | BRD4ADORA2BLMNAALDH1A1L3MBTL1 | |
| SCHEMBL23029099 | 0.70 | BRD4 (0.35) | BRD4LMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL9972888 | 0.70 | ALDH1A1 (0.40) | BRD4ADORA2BLMNAALDH1A1POLB | |
| SCHEMBL18937212 | 0.68 | L3MBTL1 (0.35) | BRD4LMNAALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093545-A1 | ANTI-BACTERIAL COMPOUNDS BASED ON AMINO-GOLD PHOSPHINE COMPLEXES | AUSPHERIX LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |