Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28778941 | 0.87 | LTA4H (0.67) | G6PC1LTA4HMAPK1TSHRACHE | |
| SCHEMBL16701049 | 0.87 | LTA4H (0.67) | G6PC1LTA4HMAPK1TSHRACHE | |
| SCHEMBL22340700 | 0.82 | TSHR (0.75) | G6PC1LTA4HMAPK1TSHRACHE | |
| SCHEMBL16516685 | 0.82 | CNR2 (0.53) | ALDH1A1CYP2A6MAPK1TSHRACHE | |
| Anisaldehyde SCHEMBL6814373 | 0.81 | ALDH1A1 (0.83) | ALDH1A1CYP2A6LTA4HBCHETDP1 | |
| Anisaldehyde SCHEMBL20357563 | 0.81 | ALDH1A1 (0.83) | ALDH1A1CYP2A6LTA4HBCHETDP1 | |
| SCHEMBL20902753 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TSHRACHEBCHENPC1 | |
| SCHEMBL9607336 | 0.79 | ALDH1A1 (0.79) | ALDH1A1CYP2A6LTA4HTSHRTDP1 | |
| SCHEMBL5270803 | 0.79 | APLNR (0.59) | ALDH1A1LTA4HMAPK1TSHRACHE | |
| SCHEMBL12049800 | 0.79 | APLNR (0.59) | ALDH1A1LTA4HMAPK1TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158657-A1 | TERTIARY AMINES FOR USE IN THE TREATMENT OF CARDIAC DISORDERS | UNIVERSITETET I OSLO (NO) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158657-A1 | TERTIARY AMINES FOR USE IN THE TREATMENT OF CARDIAC DISORDERS | TNNI3, TNNT2, MYLK2 | ALDH1A1 1367/4885CYP2A6 3367/4885G6PC1 3083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.