Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | ACP1 | P24666 | 3/20 | 0.38 |
| ▸ | CDC25B | P30305 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 13/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17356821 | 0.88 | PTPN1 (0.53) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL17356818 | 0.88 | PTPN1 (0.53) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL17351912 | 0.82 | PTPN1 (0.41) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL17351913 | 0.82 | PTPN1 (0.41) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL16012500 | 0.71 | ADORA2B (0.34) | MAPTTDP1SMN1; SMN2ADORA2B | |
| SCHEMBL18940255 | 0.70 | MAOA (0.41) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL21973203 | 0.70 | MAOA (0.41) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL21555847 | 0.69 | PTPN1 (0.40) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL20245635 | 0.67 | SMN1; SMN2 (0.50) | MAPTMAOAMAOBSMN1; SMN2 | |
| SCHEMBL18919577 | 0.65 | PTPN1 (0.48) | PTPN1ACP1CDC25BMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9463188-B2 | Osteopontin production inhibitor containing dictyopyrone derivative or dihydrodictyopyrone derivative as active ingredient | TOHOKU UNIVERSITY (JP) | 2016-10-11 | — | — | US | disclosed |
| US-9463188-B2 | Osteopontin production inhibitor containing dictyopyrone derivative or dihydrodictyopyrone derivative as active ingredient | TOHOKU UNIVERSITY (JP) | 2016-10-11 | — | — | US | disclosed |
| US-20150366851-A1 | OSTEOPONTIN PRODUCTION INHIBITOR CONTAINING DICTYOPYRONE DERIVATIVE OR DIHYDRODICTYOPYRONE DERIVATIVE AS ACTIVE INGREDIENT | TOHOKU UNIVERSITY (JP) | 2015-12-24 | — | — | US | disclosed |
| US-20150366851-A1 | OSTEOPONTIN PRODUCTION INHIBITOR CONTAINING DICTYOPYRONE DERIVATIVE OR DIHYDRODICTYOPYRONE DERIVATIVE AS ACTIVE INGREDIENT | TOHOKU UNIVERSITY (JP) | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366851-A1 | OSTEOPONTIN PRODUCTION INHIBITOR CONTAINING DICTYOPYRONE DERIVATIVE OR DIHYDRODICTYOPYRONE DERIVATIVE AS ACTIVE INGREDIENT | SPPL2B, DPYSL3, DIAPH1 | PTPN1 1624/4885ACP1 142/4885CDC25B 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.