SCHEMBL18940529

SCHEMBL18940529

CCO[Si](CCCNS(=O)(=O)C(F)(F)F)(OCC)OCC

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.54
IDO1 P14902 1/20 0.34
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
NPY5R Q15761 1/20 0.31
CA12 O43570 1/20 0.31
CA7 P43166 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28369246 0.82 CA2 (0.40) EPHX1CA1CA2
SCHEMBL28476757 0.82 CA2 (0.40) EPHX1CA1CA2
SCHEMBL12134709 0.82 EPHX1 (0.34) EPHX1
SCHEMBL3099041 0.79 POLB (0.37) CA1CA2CA12CA7CA14
SCHEMBL16566788 0.75 RELA (0.36) CA1CA2CA12CA7CA14
SCHEMBL47312 0.74 EPHX1 (0.84) EPHX1MEN1HTTKMT2ACA1
SCHEMBL18940694 0.74
SCHEMBL9105305 0.73
SCHEMBL6445621 0.73 EPHX1 (0.32) EPHX1
SCHEMBL3104136 0.73 CA12 (0.31) CA1CA2CA12CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106662820-B Composition for forming silicon-containing resist underlayer film having halosulfonylalkyl group 日产化学工业株式会社 2021-06-22 CN disclosed
US-11022884-B2 Silicon-containing resist underlayer film-forming composition having halogenated sulfonylalkyl group NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2021-06-01 US disclosed
US-20170168397-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION HAVING HALOGENATED SULFONYLALKYL GROUP NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-06-15 US disclosed