Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16770470 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPTESR2KMT2AGAA | |
| SCHEMBL31213370 | 0.84 | MAPT (0.68) | ALDH1A1MAPTESR2KMT2AGAA | |
| SCHEMBL2790591 | 0.83 | KDM4E (0.45) | ALDH1A1MAPTESR2KMT2AGAA | |
| SCHEMBL7813527 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2AGAAHTT | |
| SCHEMBL7898671 | 0.81 | KMT2A (0.49) | ALDH1A1MAPTKMT2AGAAHTT | |
| SCHEMBL9796184 | 0.81 | KDM4E (0.55) | ALDH1A1MAPTKMT2AGAAHTT | |
| SCHEMBL9796180 | 0.81 | KDM4E (0.55) | ALDH1A1MAPTKMT2AGAAHTT | |
| SCHEMBL6681734 | 0.80 | RAB9A (0.63) | ALDH1A1MAPTKMT2AGAAMEN1 | |
| SCHEMBL6681732 | 0.80 | RAB9A (0.63) | ALDH1A1MAPTKMT2AGAAMEN1 | |
| Hydrochloric Acid SCHEMBL10806635 | 0.79 | KDM4E (0.54) | ALDH1A1MAPTKMT2AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074385-B1 | PIPERIDINE DERIVATIVES FOR USE IN THE TREATMENT OR PREVENTION OF PSYCHIATRIC AND NEUROLOGICAL CONDITIONS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-12-22 | — | — | EP | disclosed |
| US-10562882-B2 | Piperidine derivatives for use in the treatment or prevention of psychiatric and neurological conditions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-02-18 | — | — | US | disclosed |
| US-20170166553-A1 | Piperidine Derivatives for Use in the Treatment or Prevention of Psychiatric and Neurological Conditions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166553-A1 | Piperidine Derivatives for Use in the Treatment or Prevention of Psychiatric and Neurological Conditions | GRIN2C, GRIN2A, PNMT | ALDH1A1 220/4885MAPT 199/4885ESR2 1027/4885 |
| US-10562882-B2 | Piperidine derivatives for use in the treatment or prevention of psychiatric and neurological conditions | GRIN2C, GRIN2A, PNMT | ALDH1A1 220/4885MAPT 199/4885ESR2 1027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.