Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18940891 | 0.91 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL18940878 | 0.89 | COMT (0.49) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL18784208 | 0.86 | TSHR (0.47) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL18784122 | 0.84 | TSHR (0.42) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| Lithium Ion SCHEMBL18784188 | 0.84 | TSHR (0.42) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| Potassium Ion SCHEMBL18784182 | 0.84 | TSHR (0.42) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL3914430 | 0.79 | MKNK1 (0.41) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL18784169 | 0.78 | TSHR (0.45) | KDM4EALDH1A1TSHRHTTCOMT | |
| SCHEMBL27804166 | 0.77 | COMT (0.44) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL8165111 | 0.77 | CA1 (0.51) | KDM4EALDH1A1HPGDTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850209-B2 | Method for manufacturing 3-(alkylsulfonyl)pyridine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20170166529-A1 | METHOD FOR MANUFACTURING 3-(ALKYLSULFONYL)PYRIDINE-2-CARBOXYLIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166529-A1 | METHOD FOR MANUFACTURING 3-(ALKYLSULFONYL)PYRIDINE-2-CARBOXYLIC ACID | HAO2, AOC2, H1-2 | KDM4E 2126/4885ALDH1A1 337/4885HSD17B10 1687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.