Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 15/20 | 0.69 |
| ▸ | LTB4R2 | Q9NPC1 | 14/20 | 0.69 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396901 | 0.82 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL1894401 | 0.82 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9022467 | 0.79 | LTB4R (0.80) | LTB4RLTB4R2MRGPRX4 | |
| SCHEMBL7959149 | 0.75 | LTB4R (0.60) | LTB4RLTB4R2MRGPRX4SRD5A2 | |
| SCHEMBL9022847 | 0.75 | LTB4R (0.84) | LTB4RLTB4R2 | |
| SCHEMBL9023332 | 0.74 | LTB4R (0.83) | LTB4RLTB4R2 | |
| SCHEMBL3363178 | 0.71 | LTB4R (0.68) | LTB4RLTB4R2 | |
| SCHEMBL4315471 | 0.68 | HTR1A (0.53) | LTB4RLTB4R2 | |
| SCHEMBL28388546 | 0.67 | LMNA (0.51) | LTB4RLTB4R2MRGPRX4SRD5A2 | |
| SCHEMBL30091828 | 0.67 | LMNA (0.51) | LTB4RLTB4R2MRGPRX4SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105959-A1 | Novel Methods for Bone Treatment by Modulating an Arachidonic Acid Metabolic or Signaling Pathway | ACCELALOX, INC. (US) | 2011-05-05 | — | — | US | disclosed |
| WO-2009105723-A2 | NOVEL METHODS FOR BONE TREATMENT BY MODULATING AN ARACHIDONIC ACID METABOLIC OR SIGNALING PATHWAY | ACCELALOX, INC. (US) | 2009-08-27 | — | — | WO | disclosed |