SCHEMBL189443

SCHEMBL189443

CC(=O)Oc1ccccc1C(=O)c1ccccc1OC(C)=O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.74
KDM4E B2RXH2 4/20 0.74
HSD17B10 Q99714 4/20 0.74
HPGD P15428 3/20 0.74
ALDH1A1 P00352 1/20 0.74
ESR1 P03372 1/20 0.74
ITGB3 P05106 1/20 0.74
ITGA2B P08514 1/20 0.74
HMGB1 P09429 1/20 0.74
TSHR P16473 1/20 0.74
GGT1 P19440 1/20 0.74
PTGS1 P23219 1/20 0.74
BLM P54132 1/20 0.74
NAPRT Q6XQN6 1/20 0.74
TDP1 Q9NUW8 1/20 0.74
LMNA P02545 1/20 0.65
CYP1A2 P05177 1/20 0.65
CYP2C9 P11712 1/20 0.65
ELANE P08246 3/20 0.63
MAPK1 P28482 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11689807 0.91 KDM4E (0.62) PTGS2KDM4EHSD17B10HPGDALDH1A1
SCHEMBL5308300 0.90 KDM4E (0.72) PTGS2KDM4EHSD17B10HPGDALDH1A1
SCHEMBL21629493 0.89 PTGS2 (0.61) PTGS2KDM4EHSD17B10HPGDALDH1A1
SCHEMBL11050544 0.87 KDM4E (0.74) PTGS2KDM4EHSD17B10HPGDALDH1A1
SCHEMBL11017487 0.87 PTGS2 (0.74) PTGS2KDM4EHSD17B10HPGDALDH1A1
SCHEMBL21629505 0.85 HPGD (0.61) PTGS2KDM4EHSD17B10HPGDALDH1A1
Aspirin SCHEMBL1331740 0.85 KDM4E (1.00) PTGS2KDM4EHSD17B10HPGDALDH1A1
Aspirin SCHEMBL7580 0.85 KDM4E (1.00) PTGS2KDM4EHSD17B10HPGDALDH1A1
SCHEMBL1369714 0.85 PTGS2 (0.71) PTGS2KDM4EHSD17B10HPGDALDH1A1
Aspirin SCHEMBL1353 0.85 KDM4E (1.00) PTGS2KDM4EHSD17B10HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2401249-B1 PROCESS FOR PRODUCING 3,4' DIHYDROXYBENZOPHENONE AS AN INTERMEDIATE FOR PRODUCING 3,4' DIACETOXYBENZOPHENONE DU PONT (US) 2013-05-15 EP claimed
EP-2401249-A1 PROCESS FOR PRODUCING 3,4' DIHYDROXYBENZOPHENONE AS AN INTERMEDIATE FOR PRODUCING 3,4' DIACETOXYBENZOPHENONE E. I. du Pont de Nemours and Company (US) 2012-01-04 EP claimed
WO-2010099144-A1 PROCESS FOR PRODUCING 3,4' DIHYDROXYBENZOPHENONE AS AN INTERMEDIATE FOR PRODUCING 3,4' DIACETOXYBENZOPHENONE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-02 WO claimed
US-7772418-B1 Process for producing 3,4′ diacetoxybenzophenone E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-10 US claimed
EP-2401249-B1 PROCESS FOR PRODUCING 3,4' DIHYDROXYBENZOPHENONE AS AN INTERMEDIATE FOR PRODUCING 3,4' DIACETOXYBENZOPHENONE DU PONT (US) 2013-05-15 EP disclosed
CN-102333751-A Process for the preparation of 3,4 '-dihydroxybenzophenone useful as an intermediate for the preparation of 3, 4' -diacetoxybenzophenone DU PONT 2012-01-25 CN disclosed
CN-102333751-A Process for the preparation of 3,4 '-dihydroxybenzophenone useful as an intermediate for the preparation of 3, 4' -diacetoxybenzophenone DU PONT 2012-01-25 CN disclosed
EP-2401249-A1 PROCESS FOR PRODUCING 3,4' DIHYDROXYBENZOPHENONE AS AN INTERMEDIATE FOR PRODUCING 3,4' DIACETOXYBENZOPHENONE E. I. du Pont de Nemours and Company (US) 2012-01-04 EP disclosed
EP-2401249-A1 PROCESS FOR PRODUCING 3,4' DIHYDROXYBENZOPHENONE AS AN INTERMEDIATE FOR PRODUCING 3,4' DIACETOXYBENZOPHENONE E. I. du Pont de Nemours and Company (US) 2012-01-04 EP disclosed
WO-2010099144-A1 PROCESS FOR PRODUCING 3,4' DIHYDROXYBENZOPHENONE AS AN INTERMEDIATE FOR PRODUCING 3,4' DIACETOXYBENZOPHENONE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-02 WO disclosed
WO-2010099144-A1 PROCESS FOR PRODUCING 3,4' DIHYDROXYBENZOPHENONE AS AN INTERMEDIATE FOR PRODUCING 3,4' DIACETOXYBENZOPHENONE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-02 WO disclosed
US-7772418-B1 Process for producing 3,4′ diacetoxybenzophenone E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-10 US disclosed
US-4983707-A Heat resistance; melt processability MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1991-01-08 US disclosed
EP-0102749-B1 FIBER-FORMING POLYESTERS OF KETODIOLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-29 EP disclosed
EP-0102749-A1 Fiber-forming polyesters of ketodiols E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-14 EP disclosed
EP-0026608-B1 AROMATIC POLYESTER AND FILAMENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-14 EP disclosed
US-4399270-A MELT SPINNABLE AND ANISTROPIC; MOLDING MATERIALS; TEXTILES; TEXTILE STRENGTH E. I. DU PONT DE NEMOURS & CO. (US) 1983-08-16 US disclosed
EP-0026608-A1 Aromatic polyester and filaments E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-04-08 EP disclosed
US-4245082-A Polyesters derived from 3,4'-dihydroxy-benzophenones or 3-hydroxy-4'-(4-hydroxyphenyl-)benzophenone and certain aromatic dicarboxylic acids and filaments thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-13 US disclosed
US-4232143-A Polyester which exhibits anisotropy in the melt containing p-oxybenzoyl units and 4,4'-dioxybenzophenone units or methyl and chloro derivatives thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-11-04 US disclosed