Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18946751 | 0.88 | ADRB2 (0.36) | ADRB2CHRM3ADRB1DRD3 | |
| SCHEMBL23223721 | 0.81 | ADRB2 (0.58) | ADRB2CHRM3ADRB1 | |
| SCHEMBL23223736 | 0.78 | ADRB2 (0.39) | ADRB2CHRM3ADRB1KDM4ELMNA | |
| SCHEMBL18946718 | 0.76 | MAOB (0.36) | PRMT5WDR77MAOBKDM4ELMNA | |
| SCHEMBL18946707 | 0.74 | ADRB2 (0.37) | ADRB2ADRB1 | |
| SCHEMBL21573538 | 0.72 | ADRB2 (0.43) | ADRB2ADRB1LMNARAB9ADRD3 | |
| SCHEMBL23198068 | 0.71 | ADRB2 (0.63) | ADRB2CHRM3ADRB1 | |
| SCHEMBL23198066 | 0.71 | ADRB2 (0.63) | ADRB2CHRM3ADRB1 | |
| SCHEMBL23198043 | 0.71 | ADRB2 (0.63) | ADRB2CHRM3ADRB1 | |
| SCHEMBL18920924 | 0.71 | ADRB2 (0.63) | ADRB2CHRM3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093208-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-06-08 | — | — | WO | disclosed |