Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 15/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23223709 | 0.88 | ADRB2 (0.39) | ADRB2ADRB1 | |
| SCHEMBL21573538 | 0.85 | ADRB2 (0.43) | ADRB2ADRB3ADRB1DRD2 | |
| SCHEMBL23223736 | 0.84 | ADRB2 (0.39) | ADRB2ADRB3ADRB1 | |
| SCHEMBL19903883 | 0.83 | ADRB2 (0.36) | ADRB2ADRB3ADRB1DRD2 | |
| SCHEMBL19903891 | 0.82 | ADRB2 (0.40) | ADRB2ADRB1DRD2 | |
| SCHEMBL19903887 | 0.81 | ADRB2 (0.32) | ADRB2ADRB3ADRB1DRD2 | |
| SCHEMBL20373657 | 0.81 | ADRB2 (0.40) | ADRB2ADRB1DRD2 | |
| SCHEMBL21573495 | 0.76 | ADRB2 (0.42) | ADRB2ADRB1DRD2 | |
| SCHEMBL19903846 | 0.75 | ADRB2 (0.36) | ADRB2ADRB3ADRB1ADRA1DDRD2 | |
| SCHEMBL18946751 | 0.74 | ADRB2 (0.36) | ADRB2ADRB3ADRB1ADRA1DDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093208-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-06-08 | — | — | WO | disclosed |