Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18946707 | 0.84 | ADRB2 (0.37) | ADRB2ADRB1ADRB3 | |
| SCHEMBL21573538 | 0.82 | ADRB2 (0.43) | ADRB2ADRB1DRD3LMNARAB9A | |
| SCHEMBL23223709 | 0.81 | ADRB2 (0.39) | ADRB2ADRB1 | |
| SCHEMBL18946751 | 0.79 | ADRB2 (0.36) | ADRB2ADRB1DRD3CHRM3ADRB3 | |
| SCHEMBL18946467 | 0.78 | ADRB2 (0.40) | ADRB2ADRB1DRD3KDM4ELMNA | |
| SCHEMBL21573522 | 0.74 | ADRB2 (0.68) | ADRB2ADRB1CHRM3 | |
| SCHEMBL19903846 | 0.74 | ADRB2 (0.36) | ADRB2ADRB1DRD3LMNARAB9A | |
| SCHEMBL20373657 | 0.74 | ADRB2 (0.40) | ADRB2ADRB1DRD3 | |
| SCHEMBL19903883 | 0.71 | ADRB2 (0.36) | ADRB2ADRB1DRD3TDP1ALDH1A1 | |
| SCHEMBL21573495 | 0.70 | ADRB2 (0.42) | ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383867-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2021-04-14 | — | — | EP | disclosed |