Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HCN1 | O60741 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18946467 | 0.76 | ADRB2 (0.40) | MAOBKDM4EPRMT5WDR77LMNA | |
| SCHEMBL21517317 | 0.66 | SLC5A1 (0.41) | KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL23223736 | 0.65 | ADRB2 (0.39) | KDM4EALDH1A1GAALMNA | |
| SCHEMBL22839931 | 0.62 | XDH (0.35) | KDM4EALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL23223711 | 0.61 | HTR2A (0.38) | — | |
| SCHEMBL14384310 | 0.60 | KMT2A (0.63) | MAOBKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL14384316 | 0.60 | PLA2G4B (0.69) | SMPD1KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL14383496 | 0.60 | PLA2G4B (0.69) | SMPD1KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL18595089 | 0.59 | PLA2G4B (0.67) | SMPD1KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL22839824 | 0.59 | HDAC1 (0.39) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093208-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-06-08 | — | — | WO | disclosed |