Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18947636 | 0.93 | GSTO1 (0.47) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPK1 | |
| SCHEMBL15076381 | 0.91 | MAPT (0.53) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPK1 | |
| SCHEMBL15076743 | 0.88 | GSTO1 (0.58) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPK1 | |
| SCHEMBL18947635 | 0.85 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPK1 | |
| SCHEMBL18947632 | 0.85 | GSTO1 (0.53) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPK1 | |
| SCHEMBL18947637 | 0.84 | CYP1A2 (0.50) | ALDH1A1SMN1; SMN2LMNAKMT2ACYP1A2 | |
| SCHEMBL15076742 | 0.84 | GSTO1 (0.56) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPK1 | |
| SCHEMBL15076462 | 0.82 | MEN1 (0.54) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPK1 | |
| SCHEMBL15076612 | 0.80 | CYP1A2 (0.46) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPK1 | |
| SCHEMBL18947640 | 0.78 | ENPP2 (0.46) | ALDH1A1LMNAKMT2ACYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676747-B2 | Hepatitis B antiviral agents | NOVIRA THERAPEUTICS, INC. (US) | 2017-06-13 | — | — | US | disclosed |