Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13241210 | 0.92 | MAPT (0.50) | ACHECLK1GSK3BDYRK1ACLK4 | |
| SCHEMBL4254063 | 0.87 | MAPT (0.49) | CLK1GSK3BDYRK1ACLK4DYRK1B | |
| SCHEMBL3054903 | 0.86 | HTT (0.49) | ACHECYP19A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL13241209 | 0.85 | OXTR (0.50) | GSK3BMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL9973674 | 0.85 | HTT (0.44) | ACHEGSK3BCYP19A1MAPTSMN1; SMN2 | |
| SCHEMBL28422697 | 0.81 | MAPT (0.44) | CLK1GSK3BDYRK1ACLK4DYRK1B | |
| SCHEMBL23382045 | 0.80 | KDM4E (0.53) | MAPTALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL13138749 | 0.79 | CYP2D6 (0.46) | CYP19A1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9912999 | 0.79 | ALDH1A1 (0.44) | ACHECLK1GSK3BDYRK1ACLK4 | |
| SCHEMBL24416475 | 0.79 | MEN1 (0.52) | ACHECYP19A1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676906-B1 | Polymer of poly(arylene ether)s, manufacturing method thereof and polymer light emitting diode with organic light emitting layer made from the same | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2017-06-13 | — | — | US | disclosed |
| US-9676906-B1 | Polymer of poly(arylene ether)s, manufacturing method thereof and polymer light emitting diode with organic light emitting layer made from the same | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2017-06-13 | — | — | US | disclosed |