SCHEMBL3054903

SCHEMBL3054903

COc1ccc(-n2c3ccc(C)cc3c3cc(C)ccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.49
HPGD P15428 3/20 0.49
MAPT P10636 3/20 0.49
PKM P14618 1/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HSD17B10 Q99714 1/20 0.49
HIF1A Q16665 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
ACHE P22303 1/20 0.48
TP53 P04637 1/20 0.48
POLB P06746 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
LMNA P02545 1/20 0.45
KDM4E B2RXH2 1/20 0.44
CUL4A Q13619 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19888132 0.91 HTT (0.46) HTTHPGDMAPTPKMALOX15
SCHEMBL12440932 0.91 HPGD (0.43) HTTHPGDMAPTPKMALOX15
SCHEMBL24416475 0.89 MEN1 (0.52) HTTHPGDMAPTPKMALOX15
SCHEMBL19888134 0.87 HTT (0.43) HTTHPGDMAPTPKMALOX15
SCHEMBL15025823 0.87 POLB (0.44) HTTHPGDMAPTPKMALOX15
SCHEMBL18947669 0.86 ACHE (0.48) HTTHPGDMAPTPKMALOX15
SCHEMBL18390943 0.85 MEN1 (0.55) HTTHPGDMAPTPKMALOX15
SCHEMBL9913062 0.85 POLB (0.46) HTTHPGDMAPTALOX15TSHR
SCHEMBL23382045 0.83 KDM4E (0.53) HTTHPGDMAPTMAPK1HSD17B10
SCHEMBL13241210 0.82 MAPT (0.50) HTTHPGDMAPTPKMALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3345983-A1 COMPOUNDS CONTAINING AT LEAST ONE DISILYL COMPOUND SELECTED FROM DISILYLCARBAZOLES, DISILYLDIBENZOFURANS, DISILYLDIBENZOTHIOPHENES, DISILYLDIBENZOPHOSPHOLES, DISILYLDIBENZOTHIOPHENE S-OXIDES AND DISILYLDIBENZOTHIOPHENE S, S-DIOXIDES UDC Ireland Limited (IE) 2018-07-11 EP disclosed
US-9676906-B1 Polymer of poly(arylene ether)s, manufacturing method thereof and polymer light emitting diode with organic light emitting layer made from the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2017-06-13 US disclosed
US-8900725-B2 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO., LTD. 2014-12-02 US disclosed
US-8859172-B2 Electrophotographic photosensitive member, method of producing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-10-14 US disclosed
US-20130137021-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2013-05-30 US disclosed
CN-101884122-B Use of diphenylamino-bis (phenoxy) triazines and bis (diphenylamino) phenoxytriazine compounds BASF SE 2012-06-06 CN disclosed
US-20120013246-A1 DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-19 US disclosed
CN-101884122-A Use of diphenylamino-bis (phenoxy) triazines and bis (diphenylamino) phenoxytriazine compounds BASF SE 2010-11-10 CN disclosed
US-20100258790-A1 USE OF DIPHENYLAMINO-BIS(PHENOXY)- AND BIS(DIPHENYLAMINO)-PHENOXYTRIAZINE COMPOUNDS BASF SE (DE) 2010-10-14 US disclosed
US-20100258790-A1 USE OF DIPHENYLAMINO-BIS(PHENOXY)- AND BIS(DIPHENYLAMINO)-PHENOXYTRIAZINE COMPOUNDS BASF SE (DE) 2010-10-14 US disclosed
US-20100258790-A1 USE OF DIPHENYLAMINO-BIS(PHENOXY)- AND BIS(DIPHENYLAMINO)-PHENOXYTRIAZINE COMPOUNDS BASF SE (DE) 2010-10-14 US disclosed
EP-2206175-A1 USE OF DIPHENYLAMINO-BIS(PHENOXY)- AND BIS(DIPHENYLAMINO)-PHENOXYTRIAZINE COMPOUNDS BASF SE (DE) 2010-07-14 EP disclosed
WO-2009053346-A1 USE OF DIPHENYLAMINO-BIS(PHENOXY)- AND BIS(DIPHENYLAMINO)-PHENOXYTRIAZINE COMPOUNDS BASF SE (DE) 2009-04-30 WO disclosed
WO-2009053346-A1 USE OF DIPHENYLAMINO-BIS(PHENOXY)- AND BIS(DIPHENYLAMINO)-PHENOXYTRIAZINE COMPOUNDS BASF SE (DE) 2009-04-30 WO disclosed
US-20080054794-A1 Organic Electroluminescence Device, Image Display Apparatus and Lighting Apparatus Including the Same, Charge Transport Material and Charge Transport Layer Forming Ink Including the Same Fujiki, Michiya (JP) 2008-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120013246-A1 DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CLTB, CD40LG, DYNLL2 HTT 4099/4885HPGD 3620/4885MAPT 446/4885
US-20100258790-A1 USE OF DIPHENYLAMINO-BIS(PHENOXY)- AND BIS(DIPHENYLAMINO)-PHENOXYTRIAZINE COMPOUNDS TRPC6, KCNB1, CACNA1I HTT 151/4885HPGD 3007/4885MAPT 263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.