Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915995 | 0.79 | FDPS (0.33) | — | |
| SCHEMBL9611561 | 0.73 | FDPS (0.34) | ALDH1A1MAPK1 | |
| SCHEMBL8918399 | 0.73 | FDPS (0.34) | — | |
| SCHEMBL755837 | 0.73 | FDPS (0.34) | ALDH1A1MAPK1 | |
| SCHEMBL8702792 | 0.73 | FDPS (0.34) | ALDH1A1MAPK1 | |
| SCHEMBL8907519 | 0.71 | FDPS (0.33) | — | |
| SCHEMBL19364536 | 0.71 | FDPS (0.33) | — | |
| SCHEMBL27586882 | 0.71 | CES2 (0.44) | CES2CES1ALDH1A1TP53CA1 | |
| SCHEMBL888837 | 0.69 | PGR (0.32) | — | |
| SCHEMBL9578928 | 0.67 | CA2 (0.61) | CA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |