Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261911 | 0.87 | ALDH1A1 (0.56) | ALDH1A1NPC1ACHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28221817 | 0.85 | ALDH1A1 (0.54) | ALDH1A1NPC1ACHEMEN1KMT2A | |
| SCHEMBL15450906 | 0.84 | KDM4E (0.51) | KDM4EPOLBALDH1A1NPC1ACHE | |
| SCHEMBL2550326 | 0.83 | L3MBTL3 (0.46) | KDM4EALDH1A1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL4720502 | 0.82 | L3MBTL3 (0.42) | MEN1KMT2ACHRM1L3MBTL3L3MBTL1 | |
| SCHEMBL2862492 | 0.81 | L3MBTL3 (0.58) | MEN1KMT2AL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL4334091 | 0.81 | L3MBTL3 (0.58) | MEN1KMT2AL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL2553841 | 0.81 | HRH3 (0.44) | KDM4EPOLBALDH1A1ALOX15L3MBTL3 | |
| SCHEMBL8004911 | 0.81 | LMNA (0.52) | KDM4EPOLBALDH1A1NPC1HTT | |
| SCHEMBL31334651 | 0.80 | CHRM1 (0.45) | ALDH1A1CHRM1L3MBTL3L3MBTL1MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9675706-B2 | Immunoconjugates with an intracellularly-cleavable linkage | IMMUNOMEDICS, INC. (US) | 2017-06-13 | — | — | US | disclosed |