Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3955545 | 0.77 | ALDH1A1 (0.65) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL6754285 | 0.71 | MAOA (0.64) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL3952458 | 0.70 | ALDH1A1 (0.77) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL28221561 | 0.70 | ALDH1A1 (0.58) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL24656203 | 0.70 | PIK3CD (0.47) | ALDH1A1MEN1KMT2AKDM4EMAOA | |
| SCHEMBL3953451 | 0.69 | ALDH1A1 (1.00) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL3948160 | 0.68 | ALDH1A1 (0.77) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL29806164 | 0.67 | RAD52 (0.53) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL5175457 | 0.67 | ALDH1A1 (0.56) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL14075916 | 0.67 | ALDH1A1 (0.71) | ALDH1A1HPGDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676769-B2 | Imidazo[4,5-C]pyridine and pyrrolo[2,3-C]pyridine derivatives as SSAO inhibitors | PROXIMAGEN LIMITED (GB) | 2017-06-13 | — | — | US | disclosed |