Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998473 | 0.89 | LMNA (0.42) | LMNAPOLBALDH1A1MAPTNPC1 | |
| SCHEMBL8961761 | 0.85 | MAPT (0.31) | LMNAMAPTRAB9AGAASMN1; SMN2 | |
| SCHEMBL28000439 | 0.81 | PIK3CD (0.35) | LMNAPOLBALDH1A1KMT2ATSHR | |
| SCHEMBL233233 | 0.81 | HPGD (0.39) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL159767 | 0.79 | HPGD (0.42) | LMNAALDH1A1MAPTNPC1HTT | |
| SCHEMBL6555355 | 0.77 | LMNA (0.32) | LMNA | |
| SCHEMBL1852924 | 0.76 | ADRA2C (0.44) | ALDH1A1MAPTKMT2ACYP1A2KDM4E | |
| SCHEMBL188699 | 0.76 | ADRB1 (0.50) | LMNAALDH1A1MAPTHTTCYP1A2 | |
| SCHEMBL3213064 | 0.76 | AR (0.37) | POLBALDH1A1MAPTRAB9ACYP1A2 | |
| SCHEMBL28431276 | 0.75 | HTT (0.46) | LMNAALDH1A1MAPTHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2109 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399198-A2 | DUAL INHIBITOR OF HISTONE DEACETYLASE 6 AND HEAT SHOCK PROTEIN 90 | Taipei Medical University (TW) | 2024-07-17 | — | — | EP | claimed |
| CN-114761406-B | Hydropyrido [1,2-a ] pyrazine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2024-04-19 | — | — | CN | claimed |
| EP-3778576-B1 | 2-CYANOPYRIMIDIN-4-YL CARBAMATE OR UREA DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | HANLIM PHARMACEUTICAL CO LTD (KR) | 2024-04-17 | — | — | EP | claimed |
| CN-115710234-B | 3,4, 5-trisubstituted isoxazole compound with anti-tumor activity and preparation method and application thereof | 华南理工大学 | 2024-04-16 | — | — | CN | claimed |
| US-20240101558-A1 | AMPK ACTIVATORS | KALLYOPE, INC. | 2024-03-28 | — | — | US | claimed |
| EP-4069693-B1 | HYDROPYRIDO[1,2-ALPHA]PYRAZINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASES | HOFFMANN LA ROCHE (CH) | 2024-03-20 | — | — | EP | claimed |
| US-11851429-B2 | AMPK activators | KALLYOPE, INC. (US) | 2023-12-26 | — | — | US | claimed |
| CN-117143158-A | Cyclic palladium catalyst precursor, cyclic palladium catalyst, preparation method and application | 宁夏中星显示材料有限公司 | 2023-12-01 | — | — | CN | claimed |
| CN-117126153-A | New coronavirus inhibitor, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-11-28 | — | — | CN | claimed |
| US-20230374014-A1 | CGAS INHIBITING TRIAZOLOPYRIMIDONE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-11-23 | — | — | US | claimed |
| WO-1997036864-A1 | BUTADIENE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1997-10-09 | — | — | WO | claimed |
| EP-0790240-A1 | Phenol-derivatives having pharmaceutical activity and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1997-08-20 | — | — | EP | claimed |
| WO-1997005877-A1 | 2-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-02-20 | — | — | WO | claimed |
| WO-1997005878-A1 | 2,5-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-02-20 | — | — | WO | claimed |
| EP-0270091-B1 | IMIDAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION OF THE SAME, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, THE USE OF THE SAME FOR THE MANUFACTURE OF MEDICAMENTS OF THERAPEUTIC VALUE, AND INTERMEDIATES FORMED DURING SAID PROCESSES | TANABE SEIYAKU CO., LTD. (JP) | 1992-11-11 | — | — | EP | claimed |
| EP-0171037-B1 | 3-CARBONYL-1-AMINOALKYL-1H-INDOLES USEFUL AS ANALGESICS AND PREPARATION THEREOF | STERLING WINTHROP INC. (US) | 1992-06-17 | — | — | EP | claimed |
| US-5002945-A | Antiulcer agents | TANABE SEIYAKU CO. LTD. (JP) | 1991-03-26 | — | — | US | claimed |
| EP-0403157-A2 | Thermal dye bleach construction | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-12-19 | — | — | EP | claimed |
| EP-0270091-A1 | Imidazole derivatives, processes for the preparation of the same, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments of therapeutic value, and intermediates formed during said processes | TANABE SEIYAKU CO., LTD. (JP) | 1988-06-08 | — | — | EP | claimed |
| US-3936564-A | Pressure-sensitive copying paper containing lactone compounds of pyridine-carboxylic acid | HODOGAYA CHEMICAL CO., LTD. (JA) | 1976-02-03 | — | — | US | claimed |