Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159767 | 0.98 | HPGD (0.42) | HPGDHSD17B10ALDH1A1TSHRMAPT | |
| SCHEMBL114701 | 0.95 | MAPK1 (0.34) | HPGDHSD17B10ALDH1A1TSHRMAPT | |
| SCHEMBL8961761 | 0.91 | MAPT (0.31) | MAPTGAASMN1; SMN2LMNARAB9A | |
| SCHEMBL188699 | 0.81 | ADRB1 (0.50) | HPGDHSD17B10ALDH1A1TSHRMAPT | |
| SCHEMBL1852924 | 0.81 | ADRA2C (0.44) | ALDH1A1MAPTKDM4EGFERGAA | |
| SCHEMBL3213064 | 0.81 | AR (0.37) | ALDH1A1MAPTL3MBTL1GAACYP1A2 | |
| SCHEMBL189494 | 0.81 | LMNA (0.50) | HPGDHSD17B10ALDH1A1TSHRMAPT | |
| SCHEMBL5655784 | 0.79 | KCNA3 (0.38) | ALDH1A1MAPTMAPK1L3MBTL1GAA | |
| SCHEMBL5423827 | 0.79 | KMT2A (0.50) | HPGDHSD17B10ALDH1A1TSHRMAPT | |
| SCHEMBL5657586 | 0.78 | KDM4E (0.39) | ALDH1A1KDM4ECYP1A2LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110128257-B | 1-phenyl-4-pentene-1-one derivative and synthesis method and application thereof | 华东师范大学 | 2021-10-15 | — | — | CN | claimed |
| US-10906919-B2 | Fused pentacyclic imidazole derivatives | UCB Biopharma SRL (BE) | 2021-02-02 | — | — | US | claimed |
| EP-3143060-B1 | CATALYSTS FOR THE SYNTHESIS OF OXAZOLIDINONE COMPOUNDS | COVESTRO DEUTSCHLAND AG (DE) | 2020-06-24 | — | — | EP | claimed |
| CN-106459331-B | For synthesizing the catalyst of Oxazolidinone compound | 科思创德国股份有限公司 | 2019-09-13 | — | — | CN | claimed |
| CN-110214133-A | N- { [2- (piperidin-1-yl) phenyl ] (phenyl) methyl } -2- (3-oxo-3, 4-dihydro-2H-1, 4-benzoxazin-7-yl) acetamide derivatives and related compounds as ROR γ modulators for the treatment of autoimmune diseases | 基恩菲特公司 | 2019-09-06 | — | — | CN | claimed |
| CN-110128257-A | 1-phenyl-4-pentene-1-one derivative and synthesis method and application thereof | 华东师范大学 | 2019-08-16 | — | — | CN | claimed |
| US-20190071416-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-03-07 | — | — | US | claimed |
| EP-3371151-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | Agency For Science, Technology And Research (SG) | 2018-09-12 | — | — | EP | claimed |
| CN-108419435-A | Compound and epigenetics for treating cancer | 新加坡科技研究局 | 2018-08-17 | — | — | CN | claimed |
| CN-108383771-A | Chiral 3,3- bis- replaces 1-isoindolinone derivative and its synthetic method and application | 华东师范大学 | 2018-08-10 | — | — | CN | claimed |
| EP-0884367-B1 | Light-writable data storage media containing cationic diphenylamine dyes | BAYER AG (DE) | 2003-08-13 | — | — | EP | claimed |
| WO-2003053443-A1 | SUBSTITUTED DIKETOPIPERAZINES AS OXYTOCIN ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2003-07-03 | — | — | WO | claimed |
| US-20030109518-A1 | Substituted 1,4-benzodiazepines and uses thereof | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-06-12 | — | — | US | claimed |
| WO-2003041715-A1 | SUBSTITUTED 1,4-BENZODIAZEPINES AND USES THEREOF FOR THE TREATMENT OF CANCER | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-05-22 | — | — | WO | claimed |
| US-6432993-B1 | BENZIMIDAZOLE OR IMIDAZO(4,5-B)PYRIDINE DERIVATES; IMMUNOMODULATORS; ALDOSE REDUCTASE AND LIPOXYGENASE INHIBITORS; DIABETES; PREVENTS LIPID PEROXIDATION; ANTILIPEMIC, HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 2002-08-13 | — | — | US | claimed |
| EP-1022272-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS | Sankyo Company Limited (JP) | 2000-07-26 | — | — | EP | claimed |
| US-5952475-A | CATIONIC THIADIAZOLEDIPHENYLAMINE DYES FOR USE IN INKJET PRINTING AND IN LIGHT-WRITABLE DATA STORAGE MEDIA AND IN DYE TRANSFER FILMS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-14 | — | — | US | claimed |
| WO-1999002532-A2 | PARTIALLY HYDROGENATED POLYCYCLIC COMPOUNDS | NOVARTIS AG (CH) | 1999-01-21 | — | — | WO | claimed |
| EP-0884367-A2 | Cationic diphenylamine dyestuffs and their anhydrobases | BAYER AG (DE) | 1998-12-16 | — | — | EP | claimed |
| EP-0051990-B1 | BIOLOGICALLY ACTIVE HETEROBICYCLIC HYDROXIMIDATES AND THIOLHYDROXIMIDATES AND CARBAMATE ESTER DERIVATIVES THEREOF | SDS BIOTECH CORPORATION (US) | 1986-01-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10906919-B2 | Fused pentacyclic imidazole derivatives | TNF, NFKBIA, TNFRSF1A | HPGD 90/4885HSD17B10 1785/4885ALDH1A1 367/4885 |
| US-20190071416-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | SMYD3, SMYD2, EHMT1 | HPGD 2786/4885HSD17B10 2834/4885ALDH1A1 373/4885 |
| US-20030109518-A1 | Substituted 1,4-benzodiazepines and uses thereof | MDM2, CBR1, ADRM1 | HPGD 1542/4885HSD17B10 627/4885ALDH1A1 1380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.