Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465609 | 0.92 | TSHR (0.45) | ALDH1A1TSHR | |
| SCHEMBL270000 | 0.83 | TSHR (0.42) | ALDH1A1TSHR | |
| SCHEMBL3957277 | 0.82 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL5702327 | 0.80 | TSHR (0.39) | ALDH1A1TSHR | |
| SCHEMBL14983 | 0.77 | TSHR (0.43) | ALDH1A1TSHR | |
| SCHEMBL8401742 | 0.77 | TSHR (0.43) | ALDH1A1TSHR | |
| SCHEMBL16295949 | 0.76 | TSHR (0.40) | ALDH1A1TSHR | |
| Iodide SCHEMBL1302038 | 0.75 | TSHR (0.42) | ALDH1A1TSHR | |
| Fluoride SCHEMBL1303213 | 0.75 | TSHR (0.42) | ALDH1A1TSHR | |
| Methyl Alcohol SCHEMBL21326729 | 0.75 | TSHR (0.42) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397505-A1 | High water content silicone hydrogels | Bausch & Lomb Incorporated (US) | 2011-12-21 | — | — | EP | disclosed |
| EP-2222736-B1 | HIGH WATER CONTENT SILICONE HYDROGELS | BAUSCH & LOMB (US) | 2011-09-21 | — | — | EP | disclosed |
| US-7934830-B2 | High water content silicone hydrogels | BAUSCH & LOMB INCORPORATED (US) | 2011-05-03 | — | — | US | disclosed |
| EP-2222736-A1 | HIGH WATER CONTENT SILICONE HYDROGELS | Bausch & Lomb Incorporated (US) | 2010-09-01 | — | — | EP | disclosed |
| EP-2121450-A1 | PACKAGING SYSTEM FOR CONTACT LENSES | Bausch & Lomb Incorporated (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2009073321-A1 | HIGH WATER CONTENT SILICONE HYDROGELS | BAUSCH & LOMB INCORPORATED (US) | 2009-06-11 | — | — | WO | disclosed |
| US-20090141234-A1 | High Water Content Silicone Hydrogels | BAUSCH HEALTH AMERICAS, INC. | 2009-06-04 | — | — | US | disclosed |
| EP-1236068-B1 | CONTACT LENS | NOVARTIS AG (CH) | 2008-08-27 | — | — | EP | disclosed |
| WO-2008079716-A1 | PACKAGING SYSTEM FOR CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 2008-07-03 | — | — | WO | disclosed |
| US-20080152540-A1 | PACKAGING SOLUTIONS | BAUSCH & LOMB INCORPORATED (US) | 2008-06-26 | — | — | US | disclosed |
| US-7201481-B2 | Interpolymerization product of a (a) hydrophilic monomer with (b) a tris(siloxy)silyl group- containing monomer, (c) a wide variety of hydrophobic monomers (both aliphatic and aromatic) and usually a (d) polyfluorinated monomer | NOVARTIS AG (CH) | 2007-04-10 | — | — | US | disclosed |
| EP-1236068-A4 | CONTACT LENS | NOVARTIS AG (CH) | 2007-03-28 | — | — | EP | disclosed |
| US-20060012751-A1 | Contact lens | ALCON INC. (CH) | 2006-01-19 | — | — | US | disclosed |
| US-6649722-B2 | Interpolymerization product of a (a) hydrophilic monomer with (b) a tris(siloxy)silyl group- containing monomer, (c) a wide variety of hydrophobic monomers (both aliphatic and aromatic) and usually a (d) polyfluorinated monomer | NOVARTIS AG (CH) | 2003-11-18 | — | — | US | disclosed |
| EP-1236068-A1 | CONTACT LENS | Novartis AG (CH) | 2002-09-04 | — | — | EP | disclosed |
| US-20020107337-A1 | Contact lens | ALCON INC. (CH) | 2002-08-08 | — | — | US | disclosed |
| WO-2001042846-A1 | CONTACT LENS | WESLEY JESSEN CORPORATION (US) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080152540-A1 | PACKAGING SOLUTIONS | AQP1, ARGLU1, CRYZ | ALDH1A1 4081/4885TSHR 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.