Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405521 | 0.81 | HSD17B10 (0.61) | HSD17B10PLA2G10ALDH1A1TSHRFGFR1 | |
| SCHEMBL12094386 | 0.80 | HAO1 (0.55) | HSD17B10PLA2G10ALDH1A1TSHRFGFR1 | |
| SCHEMBL18950565 | 0.76 | HSD17B10 (0.70) | HSD17B10ALDH1A1FGFR1KDM4EL3MBTL1 | |
| SCHEMBL14867768 | 0.76 | ALDH1A1 (0.55) | PLA2G10ALDH1A1TSHRKDM4EL3MBTL1 | |
| SCHEMBL22468952 | 0.71 | PLA2G4A (0.58) | HSD17B10PLA2G10FGFR1KDM4EHPGD | |
| SCHEMBL31416092 | 0.71 | KDM4E (0.69) | HSD17B10ALDH1A1TSHRFGFR1KDM4E | |
| SCHEMBL21760735 | 0.71 | KDM4E (0.69) | HSD17B10ALDH1A1TSHRFGFR1KDM4E | |
| SCHEMBL28325715 | 0.70 | HSD17B10 (0.46) | HSD17B10PLA2G10ALDH1A1TSHRFGFR1 | |
| SCHEMBL120600 | 0.70 | HSD17B10 (1.00) | HSD17B10ALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL28325704 | 0.70 | PLA2G10 (0.50) | HSD17B10PLA2G10ALDH1A1TSHRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9675584-B2 | Substituted indoles for the inhibition of PASK | BIOENERGENIX, LLC (US) | 2017-06-13 | — | — | US | disclosed |