Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612323 | 0.81 | CSNK1A1 (0.55) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL3236957 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL27716588 | 0.79 | CSNK1A1 (0.53) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL12813320 | 0.77 | ALDH1A1 (0.42) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL10567682 | 0.74 | XDH (0.51) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL28145391 | 0.74 | ADORA2A (0.59) | XDHCSNK1A1CLK4ADORA1ADORA2A | |
| Hydrochloric Acid SCHEMBL12813303 | 0.74 | RAB9A (0.41) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL23009764 | 0.73 | KDM4E (0.71) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL4559392 | 0.71 | XDH (0.42) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL12014939 | 0.71 | KDM4E (0.68) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555095-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018157830-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-09-07 | — | — | WO | disclosed |
| EP-3362451-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-08-22 | — | — | EP | disclosed |
| WO-2018127096-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018108125-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-06-21 | — | — | WO | disclosed |
| WO-2017097234-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-06-15 | — | — | WO | disclosed |