Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14357523 | 0.92 | LMNA (0.58) | LMNAL3MBTL1TDP1KDM4ETSHR | |
| SCHEMBL28074966 | 0.90 | TDP1 (0.60) | LMNAL3MBTL1TDP1KDM4ETSHR | |
| SCHEMBL18884929 | 0.90 | TDP1 (0.60) | LMNAL3MBTL1TDP1KDM4ETSHR | |
| SCHEMBL28074964 | 0.90 | TDP1 (0.60) | LMNAL3MBTL1TDP1KDM4ETSHR | |
| SCHEMBL270330 | 0.82 | — | — | |
| SCHEMBL16280836 | 0.82 | TSHR (0.44) | TDP1TSHRTRPA1 | |
| SCHEMBL13638247 | 0.82 | LMNA (0.59) | LMNAL3MBTL1TDP1KDM4ETSHR | |
| SCHEMBL13536696 | 0.82 | — | — | |
| SCHEMBL106965 | 0.82 | TSHR (0.44) | TDP1TSHRTRPA1 | |
| SCHEMBL11923038 | 0.82 | LMNA (0.59) | LMNAL3MBTL1TDP1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180362456-A1 | NEW COMPOUNDS WITH ANTIOXIDANT AND ANTIAGING ACTIVITY | EMS S/A (BR) | 2018-12-20 | — | — | US | disclosed |
| WO-2017096450-A1 | NEW COMPOUNDS WITH ANTIOXIDANT AND ANTIAGING ACTIVITY | EMS S/A (BR) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180362456-A1 | NEW COMPOUNDS WITH ANTIOXIDANT AND ANTIAGING ACTIVITY | GPX1, CAT, GPX4 | LMNA 1674/4885L3MBTL1 2608/4885TDP1 800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.