Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 10/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15536746 | 0.90 | MMP13 (0.41) | MMP13SLC22A12HRH3NPBWR1MCHR1 | |
| SCHEMBL18952978 | 0.85 | MMP13 (0.40) | MMP13SLC22A12HRH3RET | |
| SCHEMBL1980366 | 0.81 | AR (0.36) | MMP13SLC22A12NPBWR1MCHR1 | |
| SCHEMBL1982561 | 0.80 | AR (0.47) | MMP13SLC22A12 | |
| SCHEMBL19805335 | 0.79 | HRH3 (0.32) | MMP13SLC22A12HRH3NPBWR1MCHR1 | |
| SCHEMBL18952979 | 0.79 | MMP13 (0.41) | MMP13 | |
| SCHEMBL12594113 | 0.78 | AR (0.38) | MMP13SLC22A12NPBWR1MCHR1 | |
| SCHEMBL18952992 | 0.77 | MMP13 (0.39) | MMP13 | |
| SCHEMBL1981227 | 0.76 | ALDH1A1 (0.37) | SLC22A12HRH3NPBWR1MCHR1KDM5A | |
| SCHEMBL29384188 | 0.76 | ALDH1A1 (0.37) | SLC22A12HRH3NPBWR1MCHR1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386506-A1 | MODULATORS OF KV3 CHANNELS TO TREAT PAIN | Autifony Therapeutics Limited (GB) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017098254-A1 | MODULATORS OF KV3 CHANNELS TO TREAT PAIN | AUTIFONY THERAPEUTICS LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |