SCHEMBL18952971

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18952972	0.96	KDM4E (0.42)	HSD11B1EPAS1CFTRL3MBTL1SDHB
	SCHEMBL16513114	0.92	HSD11B1 (0.50)	HSD11B1EPAS1CFTRL3MBTL1SDHB
	SCHEMBL852699	0.91	KDM4E (0.48)	HSD11B1EPAS1L3MBTL1SDHBKDM4E
	SCHEMBL31150577	0.91	KDM4E (0.48)	HSD11B1EPAS1L3MBTL1SDHBKDM4E
	SCHEMBL14063330	0.89	HSD11B1 (0.46)	HSD11B1EPAS1L3MBTL1CXCR2KDM4E
	SCHEMBL17877014	0.89	HSD11B1 (0.43)	HSD11B1EPAS1CFTRL3MBTL1CXCR2
	SCHEMBL17913590	0.88	EPAS1 (0.45)	HSD11B1EPAS1KDM4EMEN1KMT2A
	SCHEMBL27229877	0.85	KDM4E (0.41)	HSD11B1EPAS1CFTRL3MBTL1SDHB
	SCHEMBL7214605	0.84	KDM4E (0.49)	HSD11B1EPAS1L3MBTL1SDHBKDM4E
	SCHEMBL974920	0.82	HSD11B1 (0.45)	HSD11B1EPAS1CFTRL3MBTL1SDHB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.