Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SDHB | P21912 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18952971 | 0.96 | HSD11B1 (0.41) | KDM4EALDH1A1HPGDHSD11B1EPAS1 | |
| SCHEMBL16513114 | 0.88 | HSD11B1 (0.50) | KDM4EALDH1A1HPGDHSD11B1EPAS1 | |
| SCHEMBL31150577 | 0.87 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD11B1EPAS1 | |
| SCHEMBL852699 | 0.87 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD11B1EPAS1 | |
| SCHEMBL14063330 | 0.85 | HSD11B1 (0.46) | KDM4EALDH1A1HSD11B1EPAS1HSD17B10 | |
| SCHEMBL17877014 | 0.85 | HSD11B1 (0.43) | KDM4EALDH1A1HPGDHSD11B1EPAS1 | |
| SCHEMBL17913590 | 0.84 | EPAS1 (0.45) | KDM4EHSD11B1EPAS1HSD17B10MEN1 | |
| SCHEMBL27229877 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1HSD11B1EPAS1CFTR | |
| SCHEMBL7214605 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD11B1EPAS1 | |
| SCHEMBL7654198 | 0.79 | RAB9A (0.44) | KDM4EALDH1A1HPGDEPAS1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793668-B2 | Naphthoindacenodithiophenes and polymers | CLAP CO., LTD. (KR) | 2020-10-06 | — | — | US | disclosed |
| EP-3386989-B1 | NAPHTHOINDACENODITHIOPHENES AND POLYMERS | BASF SE (DE) | 2019-10-23 | — | — | EP | disclosed |
| US-20180362704-A1 | NAPHTHOINDACENODITHIOPHENES AND POLYMERS | BASF SE (DE) | 2018-12-20 | — | — | US | disclosed |
| EP-3386989-A1 | NAPHTHOINDACENODITHIOPHENES AND POLYMERS | BASF SE (DE) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017097924-A1 | NAPHTHOINDACENODITHIOPHENES AND POLYMERS | BASF SE (DE) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793668-B2 | Naphthoindacenodithiophenes and polymers | RPS21, NR2C2, NR0B2 | KDM4E 4743/4885ALDH1A1 1958/4885HPGD 1527/4885 |
| US-20180362704-A1 | NAPHTHOINDACENODITHIOPHENES AND POLYMERS | RPS21, NR2C2, NR0B2 | KDM4E 4743/4885ALDH1A1 1958/4885HPGD 1527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.