Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18201985 | 0.72 | THRB (0.40) | KMT2AMAPTMEN1MAPK1THRB | |
| SCHEMBL7347411 | 0.69 | THRB (0.47) | KMT2ATHRBPPARGPPARAALDH1A1 | |
| SCHEMBL18952922 | 0.67 | KMT2A (0.70) | KMT2AMAPTMEN1LMNAHTT | |
| SCHEMBL5701898 | 0.63 | THRB (0.42) | KMT2AMAPTTHRBPPARGPPARA | |
| SCHEMBL4137878 | 0.63 | PPARG (0.49) | KMT2ATHRBPPARGPPARAALDH1A1 | |
| SCHEMBL7903010 | 0.63 | POLB (0.53) | KMT2ALMNAGAATHRBPPARG | |
| SCHEMBL12611654 | 0.62 | LMNA (0.61) | KMT2AMAPTMEN1LMNAGAA | |
| SCHEMBL3719181 | 0.62 | MEN1 (0.45) | KMT2AMAPTMEN1LMNAALOX15 | |
| SCHEMBL5272244 | 0.62 | PPARG (0.48) | KMT2ALMNATHRBPPARGPPARA | |
| SCHEMBL8699347 | 0.62 | THRB (0.39) | KMT2AMAPTHTTTHRBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386498-A1 | METHOD FOR MODULATING AUTOPHAGY AND APPLICATIONS THEREOF | Jawaharlal Nehru Centre For Advanced Scientific Research (IN) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017098467-A1 | METHOD FOR MODULATING AUTOPHAGY AND APPLICATIONS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2017-06-15 | — | — | WO | disclosed |