Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 4/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954828 | 0.84 | CHRM5 (0.54) | CHRM5ALDH1A1ALDH3A1FABP3KMT2A | |
| SCHEMBL18954698 | 0.81 | MAPT (0.56) | ALDH1A1KMT2AMEN1TGM2 | |
| SCHEMBL18954783 | 0.81 | CTRC (0.52) | CHRM5ALDH1A1ALDH2ALDH3A1CHRM3 | |
| SCHEMBL18954872 | 0.81 | CHRM5 (0.55) | CHRM5ALDH1A1ALDH2ALDH3A1CHRM3 | |
| SCHEMBL27866582 | 0.81 | ALDH1A1 (0.67) | CHRM5ALDH1A1ALDH2ALDH3A1CHRM3 | |
| SCHEMBL18955196 | 0.79 | GAA (0.48) | CHRM5ALDH1A1FABP4KMT2APARK7 | |
| SCHEMBL18974327 | 0.78 | CES1 (0.62) | CHRM5ALDH1A1ALDH2ALDH3A1CHRM3 | |
| SCHEMBL18954645 | 0.75 | ALDH1A1 (0.51) | CHRM5ALDH1A1ALDH2ALDH3A1CHRM3 | |
| SCHEMBL18954806 | 0.75 | PARK7 (0.60) | CHRM5ALDH1A1ALDH2ALDH3A1PARK7 | |
| SCHEMBL31751956 | 0.74 | KMT2A (0.56) | ALDH1A1GRM5KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |