Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954698 | 0.84 | MAPT (0.56) | TP53MAPTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL18954828 | 0.81 | CHRM5 (0.54) | PARK7ALDH1A1CHRM5TGM2KMT2A | |
| SCHEMBL18954783 | 0.81 | CTRC (0.52) | TP53MAPTSMN1; SMN2PARK7ALDH1A1 | |
| SCHEMBL18954872 | 0.81 | CHRM5 (0.55) | TP53MAPTPARK7ALDH1A1CHRM5 | |
| SCHEMBL18955264 | 0.79 | KMT2A (0.54) | KDM4ETP53MAPTSMN1; SMN2PARK7 | |
| SCHEMBL18955277 | 0.79 | PARK7 (0.63) | KDM4ETP53MAPTPARK7ALDH1A1 | |
| SCHEMBL18954595 | 0.79 | CHRM5 (0.53) | PARK7ALDH1A1FABP4CHRM5TGM2 | |
| SCHEMBL18974327 | 0.78 | CES1 (0.62) | TP53MAPTPARK7ALDH1A1CHRM5 | |
| SCHEMBL18954555 | 0.75 | MAPT (0.47) | TP53MAPTSMN1; SMN2PARK7L3MBTL1 | |
| SCHEMBL18954645 | 0.75 | ALDH1A1 (0.51) | TP53MAPTPARK7ALDH1A1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |