Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 4/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.38 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954759 | 0.93 | PARK7 (0.50) | PARK7ALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL9179332 | 0.87 | ALDH1A1 (0.62) | PARK7ALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL18954749 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTHTTHSD17B10ALDH3A1 | |
| SCHEMBL18954460 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTHSD17B10ALDH2 | |
| SCHEMBL18954588 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTHTTHSD17B10TP53 | |
| SCHEMBL18955261 | 0.74 | ALDH1A1 (0.58) | PARK7ALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL18954792 | 0.73 | PARK7 (0.44) | PARK7ALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL18954539 | 0.73 | ALDH1A1 (0.62) | PARK7ALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL18954738 | 0.73 | PARK7 (0.50) | PARK7ALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL4737553 | 0.73 | PARK7 (0.59) | PARK7ALDH1A1MAPTALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |