Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | ALDH2 | P05091 | 5/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784867 | 0.75 | PARK7 (0.82) | PARK7ALDH1A1ALDH2ALDH3A1TP53 | |
| SCHEMBL4785743 | 0.74 | PARK7 (1.00) | PARK7ALDH1A1ALDH2ALDH3A1CASP3 | |
| SCHEMBL18954539 | 0.74 | ALDH1A1 (0.62) | PARK7ALDH1A1ALDH2ALDH3A1TP53 | |
| SCHEMBL9179440 | 0.74 | PARK7 (0.51) | PARK7ALDH1A1ALDH2ALDH3A1TP53 | |
| SCHEMBL18954746 | 0.73 | PARK7 (0.52) | PARK7ALDH1A1ALDH2ALDH3A1TP53 | |
| SCHEMBL4737000 | 0.73 | PARK7 (0.55) | PARK7ALDH1A1ALDH2ALDH3A1TP53 | |
| SCHEMBL4784991 | 0.72 | PARK7 (0.81) | PARK7ALDH1A1ALDH2ALDH3A1TP53 | |
| SCHEMBL4786048 | 0.72 | PARK7 (0.78) | PARK7ALDH1A1ALDH2ALDH3A1TP53 | |
| SCHEMBL30774299 | 0.72 | PARK7 (0.82) | PARK7ALDH1A1ALDH2ALDH3A1TP53 | |
| SCHEMBL4739092 | 0.72 | PARK7 (0.82) | PARK7ALDH1A1ALDH2ALDH3A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074078-A1 | SELECTIVELY DELIVERABLE ISATIN-BASED CYTOTOXIC AGENTS | UNIVERSITY OF WOLLONGONG (AU) | 2008-06-26 | — | — | WO | disclosed |