Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 6/20 | 0.50 |
| ▸ | CASP7 | P55210 | 6/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954856 | 0.92 | CASP3 (0.57) | CASP3CASP7CA12CA1CA2 | |
| SCHEMBL18954750 | 0.87 | CA12 (0.48) | CASP3CASP7CA12CA1CA2 | |
| SCHEMBL18954661 | 0.84 | CASP3 (0.53) | CASP3CASP7CA12CA1CA2 | |
| SCHEMBL18955348 | 0.83 | ALDH1A1 (0.53) | CASP3CASP7MEN1KMT2ACASP1 | |
| SCHEMBL18954857 | 0.79 | CASP3 (0.54) | CASP3CASP7CA12CA1CA2 | |
| SCHEMBL18955307 | 0.78 | ALDH1A1 (0.55) | CASP3CASP7CA12CA1CA2 | |
| SCHEMBL4625283 | 0.78 | CA1 (0.49) | CASP3CASP7CA12CA1CA2 | |
| SCHEMBL18974999 | 0.76 | CES1 (0.67) | MEN1KMT2APARK7APEX1 | |
| SCHEMBL19000856 | 0.76 | PARK7 (0.60) | CASP3CASP7CA12CA1CA2 | |
| SCHEMBL18954686 | 0.75 | CA1 (0.57) | CASP3CASP7CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |