Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CASP3 | P42574 | 11/20 | 0.46 |
| ▸ | CASP7 | P55210 | 11/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18955307 | 0.93 | ALDH1A1 (0.55) | ALDH1A1CASP3CASP7CASP1CASP6 | |
| SCHEMBL18955347 | 0.89 | ALDH1A1 (0.53) | ALDH1A1CASP3CASP7CASP1CASP6 | |
| SCHEMBL18955190 | 0.89 | CA1 (0.54) | ALDH1A1CASP3CASP7 | |
| SCHEMBL18955210 | 0.86 | ALDH1A1 (0.71) | ALDH1A1CASP3CASP7MAPTKMT2A | |
| SCHEMBL18954612 | 0.85 | ALDH1A1 (0.73) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL18954748 | 0.83 | CASP3 (0.50) | CASP3CASP7CASP1CASP6KMT2A | |
| SCHEMBL18954685 | 0.83 | PARK7 (0.58) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL18954676 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL18955310 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CASP3MAPTKMT2AMEN1 | |
| SCHEMBL18955159 | 0.82 | PARK7 (0.56) | ALDH1A1MAPTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |