Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.42 |
| ▸ | CA1 | P00915 | 10/20 | 0.42 |
| ▸ | CA9 | Q16790 | 10/20 | 0.42 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA7 | P43166 | 4/20 | 0.42 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
| ▸ | CA5A | P35218 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16041473 | 0.73 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL29581330 | 0.71 | CA2 (0.49) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7633146 | 0.71 | CA2 (0.49) | CA2CA1CA9CA12CA7 | |
| SCHEMBL2117356 | 0.71 | CA2 (0.67) | CA2CA1CA9CA12CA7 | |
| SCHEMBL29469920 | 0.71 | CA2 (0.67) | CA2CA1CA9CA12CA7 | |
| SCHEMBL27989103 | 0.70 | CA2 (0.40) | CA2CA1CA9CA12CA7 | |
| SCHEMBL1520893 | 0.69 | SIGMAR1 (0.43) | ALDH1A1 | |
| SCHEMBL10800256 | 0.69 | TTR (0.42) | CA2CA1CA9CA5AALDH1A1 | |
| SCHEMBL18092286 | 0.69 | NPSR1 (0.42) | CA2CA1CA9CA12CA7 | |
| SCHEMBL202947 | 0.68 | CA2 (0.70) | CA2CA1CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |