Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20194482 | 0.98 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL28921103 | 0.89 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL3598057 | 0.86 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1KMT2ANLRP3MEN1 | |
| SCHEMBL6430240 | 0.85 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL18415481 | 0.85 | KMT2A (0.59) | ALDH1A1NPC1RAB9AKMT2ANLRP3 | |
| SCHEMBL19781758 | 0.83 | NLRP3 (0.53) | ALDH1A1L3MBTL1KMT2ANLRP3MEN1 | |
| SCHEMBL17845245 | 0.82 | LMNA (0.49) | ALDH1A1L3MBTL1KMT2ANLRP3MEN1 | |
| SCHEMBL20362848 | 0.82 | PDK1 (0.50) | ALDH1A1L3MBTL1RAB9AKMT2ANLRP3 | |
| SCHEMBL26409973 | 0.82 | KMT2A (0.52) | ALDH1A1NPC1RAB9AKMT2ANLRP3 | |
| SCHEMBL25249826 | 0.80 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1NLRP3CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4431180-A2 | OLEFIN METATHESIS CATALYSTS | Umicore AG & Co. KG (DE) | 2024-09-18 | — | — | EP | disclosed |
| US-20210053043-A1 | OLEFIN METATHESIS CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2021-02-25 | — | — | US | disclosed |
| US-20210053043-A1 | OLEFIN METATHESIS CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2021-02-25 | — | — | US | disclosed |
| US-10857530-B2 | Olefin metathesis catalysts | UMICORE AG & CO. KG (DE) | 2020-12-08 | — | — | US | disclosed |
| US-10857530-B2 | Olefin metathesis catalysts | UMICORE AG & CO. KG (DE) | 2020-12-08 | — | — | US | disclosed |
| US-20180361371-A1 | OLEFIN METATHESIS CATALYSTS | UMICORE AG & CO KG (DE) | 2018-12-20 | — | — | US | disclosed |
| EP-3386936-A1 | OLEFIN METATHESIS CATALYSTS | Umicore AG & Co. KG (DE) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017100585-A1 | OLEFIN METATHESIS CATALYSTS | MATERIA, INC. (US) | 2017-06-15 | — | — | WO | disclosed |
| WO-2017100585-A1 | OLEFIN METATHESIS CATALYSTS | MATERIA, INC. (US) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10857530-B2 | Olefin metathesis catalysts | ZDHHC7, ZDHHC2, OSBP | ALDH1A1 1629/4885L3MBTL1 774/4885NPC1 891/4885 |
| US-20210053043-A1 | OLEFIN METATHESIS CATALYSTS | ZDHHC7, ZDHHC2, OSBP | ALDH1A1 1629/4885L3MBTL1 774/4885NPC1 891/4885 |
| US-20180361371-A1 | OLEFIN METATHESIS CATALYSTS | ZDHHC7, ZDHHC2, OSBP | ALDH1A1 1629/4885L3MBTL1 774/4885NPC1 891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.