Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 3/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 2/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23176766 | 0.81 | RAB9A (0.59) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL30288200 | 0.79 | NPC1 (0.49) | TTRCASP3SENP8SENP7SENP6 | |
| Methyl Alcohol SCHEMBL27795304 | 0.79 | NPC1 (0.45) | RAB9ANPC1HPGDHSD17B10KDM4E | |
| SCHEMBL12794312 | 0.79 | EDNRB (0.39) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL13086663 | 0.78 | NPC1 (0.60) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL1207825 | 0.78 | NPC1 (0.45) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL5540045 | 0.78 | KDM4E (0.59) | RAB9ANPC1HPGDHSD17B10KDM4E | |
| SCHEMBL2288771 | 0.78 | C1R (0.43) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL19484241 | 0.77 | RAB9A (0.65) | RAB9ANPC1KDM4ETSHRKMT2A | |
| SCHEMBL10186915 | 0.77 | PDCD1 (0.42) | CASP3SENP8SENP7SENP6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119968377-A | Phosphoramidate compounds and uses thereof | 安锐生物医药公司 | 2025-05-09 | — | — | CN | disclosed |
| US-11638706-B2 | Methods for treating Huntington's disease | PTC THERAPEUTICS, INC. (US) | 2023-05-02 | — | — | US | disclosed |
| US-11608501-B2 | Methods for modifying RNA splicing | PTC THERAPEUTICS, INC. (US) | 2023-03-21 | — | — | US | disclosed |
| EP-3638318-A1 | METHODS FOR MODIFYING RNA SPLICING | PTC Therapeutics, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| WO-2018232039-A1 | METHODS FOR MODIFYING RNA SPLICING | PTC THERAPEUTICS, INC. (US) | 2018-12-20 | — | — | WO | disclosed |
| EP-3386511-A1 | METHODS FOR TREATING HUNTINGTON'S DISEASE | PTC Therapeutics, Inc. (US) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017100726-A1 | METHODS FOR TREATNG HUNTINGTON'S DISEASE | PTC THERAPEUTICS, INC. (US) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11608501-B2 | Methods for modifying RNA splicing | RBM17, SNRPA1, SNRPE | TTR 3302/4885CASP3 4188/4885SENP8 2039/4885 |
| US-11638706-B2 | Methods for treating Huntington's disease | HTT, HYPK, FH | TTR 27/4885CASP3 1949/4885SENP8 2364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.