Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.62 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.61 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.60 |
| ▸ | SCN4A | P35499 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | TDO2 | P48775 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524687 | 0.91 | NOS2 (0.50) | NOS2CHRNB2CHRNA4SLC6A4SCN4A | |
| Hydrochloric Acid SCHEMBL3521179 | 0.89 | NOS2 (0.49) | NOS2CHRNB2CHRNA4SLC6A4SCN4A | |
| SCHEMBL3034916 | 0.87 | SLC6A4 (0.55) | NOS2CHRNB2CHRNA4SLC6A4SCN4A | |
| SCHEMBL7049684 | 0.86 | SLC6A4 (0.66) | NOS2CHRNB2CHRNA4SLC6A4SCN4A | |
| Hydrogen Sulfide SCHEMBL27817937 | 0.85 | SLC6A4 (0.53) | NOS2CHRNB2CHRNA4SLC6A4SLC6A2 | |
| SCHEMBL17278127 | 0.82 | SLC7A5 (0.68) | NOS2SLC6A4SLC6A2SLC6A3KCNK2 | |
| SCHEMBL11750036 | 0.82 | SLC6A4 (0.60) | CHRNB2CHRNA4SLC6A4SCN4ASLC6A9 | |
| SCHEMBL350781 | 0.82 | SLC6A4 (0.60) | NOS2SLC6A4SLC6A2SLC6A3KCNK2 | |
| Oxalic Acid SCHEMBL7318674 | 0.80 | SLC6A4 (0.61) | NOS2SLC6A4SLC6A2SLC6A3KCNK2 | |
| SCHEMBL17487302 | 0.79 | SLC6A4 (0.61) | NOS2CHRNB2CHRNA4SLC6A4SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170166563-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166563-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | ALOX5, ALOX15, ALOX12 | NOS2 153/4885CHRNB2 665/4885CHRNA4 469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.