Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.61 |
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ATG4B | Q9Y4P1 | 5/20 | 0.59 |
| ▸ | STAT3 | P40763 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nithiamide SCHEMBL158858 | 0.83 | NPC1 (0.63) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL3234255 | 0.81 | ATG4B (0.68) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL3234242 | 0.81 | ATG4B (0.67) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL3466003 | 0.80 | LMNA (0.67) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL881339 | 0.80 | LMNA (0.84) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL12599400 | 0.80 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL19906418 | 0.80 | ATG4B (0.65) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL18424530 | 0.80 | ATG4B (0.69) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL27671732 | 0.79 | NPC1 (0.55) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL4748802 | 0.79 | ALDH1A1 (0.58) | NPC1RAB9AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168536-A1 | METHODS AND COMPOSITIONS FOR CULTIVATING PLURIPOTENT CELL SUSPENSIONS | Life Technologies Corporation (US) | 2023-04-26 | — | — | EP | claimed |
| WO-2025106671-A1 | PERSONALIZED PROGENITOR CELLS | IMMORTA BIO, INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| US-20240252688-A1 | COMPOSITIONS AND METHODS FOR ENHANCED PROTEIN PRODUCTION | HDT BIO CORP. | 2024-08-01 | — | — | US | disclosed |
| EP-4178594-A1 | A METHOD FOR GENERATING A THREE-DIMENSIONAL NEUROMUSCULAR ORGANOID IN VITRO | Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (DE) | 2023-05-17 | — | — | EP | disclosed |
| EP-4153726-A1 | METHOD FOR GENERATING FUNCTIONAL SKELETAL MUSCLE FIBERS INNERVATED BY MOTONEURONS | Association Française contre les Myopathies (AFM) (FR) | 2023-03-29 | — | — | EP | disclosed |
| CN-104130976-A | Generation and maintenance of stem cells | SCRIPPS RESEARCH INST | 2014-11-05 | — | — | CN | disclosed |
| CN-102317442-B | Production and maintenance of stem cells | SCRIPPS RESEARCH INST | 2014-08-13 | — | — | CN | disclosed |
| US-8796182-B2 | Genetic markers associated with risk of diabetes mellitus | DECODE GENETICS EHF. (IS) | 2014-08-05 | — | — | US | disclosed |
| US-20120220477-A1 | GENETIC MARKERS ASSOCIATED WITH RISK OF DIABETES MELLITUS | DECODE GENETICS EHF. (IS) | 2012-08-30 | — | — | US | disclosed |
| WO-2011109015-A1 | IMPROVED METHODS OF GENERATING PLURIPOTENT STEM CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-09-09 | — | — | WO | disclosed |
| WO-2011056971-A2 | EPISOMAL REPROGRAMMING WITH CHEMICALS | CELLULAR DYNAMICS INTERNATIONAL, INC. (US) | 2011-05-12 | — | — | WO | disclosed |