Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.67 |
| ▸ | RAB9A | P51151 | 8/20 | 0.66 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 9/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | HTT | P42858 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | NPY1R | P25929 | 1/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 5/20 | 0.59 |
| ▸ | ALPL | P05186 | 3/20 | 0.58 |
| ▸ | ALPI | P09923 | 2/20 | 0.58 |
| ▸ | ALPG | P10696 | 2/20 | 0.58 |
| ▸ | CASP6 | P55212 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881339 | 0.85 | LMNA (0.84) | LMNARAB9AMAPTNPC1MEN1 | |
| SCHEMBL18424530 | 0.85 | ATG4B (0.69) | LMNARAB9AMAPTNPC1MEN1 | |
| SCHEMBL5836289 | 0.82 | LMNA (0.85) | LMNARAB9AMAPTNPC1MEN1 | |
| SCHEMBL14906480 | 0.81 | LMNA (0.74) | LMNARAB9AMAPTNPC1MEN1 | |
| SCHEMBL1395039 | 0.80 | LMNA (1.00) | LMNARAB9AMAPTNPC1MEN1 | |
| SCHEMBL375490 | 0.80 | LMNA (0.76) | LMNARAB9AMAPTNPC1MEN1 | |
| Nithiamide SCHEMBL158858 | 0.80 | NPC1 (0.63) | LMNARAB9AMAPTNPC1MEN1 | |
| SCHEMBL1896161 | 0.80 | NPC1 (0.61) | LMNARAB9AMAPTNPC1MEN1 | |
| SCHEMBL13694246 | 0.79 | MEN1 (0.77) | LMNARAB9AMAPTNPC1MEN1 | |
| Hydrochloric Acid SCHEMBL28533675 | 0.79 | LMNA (0.74) | LMNARAB9AMAPTNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200140460-A1 | ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS | VYOME BIOSCIENCES PVT. LTD. (IN) | 2020-05-07 | — | — | US | disclosed |
| US-10570152-B2 | Antibacterial therapeutics and prophylactics | VYOME THERAPEUTICS LIMITED (IN) | 2020-02-25 | — | — | US | disclosed |
| US-20180265523-A1 | ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS | VYOME THERAPEUTICS LIMITED (IN) | 2018-09-20 | — | — | US | disclosed |
| EP-3328856-A2 | ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS | Vyome Biosciences Pvt. Ltd. (IN) | 2018-06-06 | — | — | EP | disclosed |
| WO-2017017631-A2 | ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS | VYOME BIOSCIENCES PVT. LTD. (IN) | 2017-02-02 | — | — | WO | disclosed |
| WO-2017017631-A2 | ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS | VYOME BIOSCIENCES PVT. LTD. (IN) | 2017-02-02 | — | — | WO | disclosed |
| US-7678791-B2 | Nitroheteroaryl-containing rifamycin derivatives | CUMBRE IP VENTURES, L.P. (US) | 2010-03-16 | — | — | US | disclosed |
| US-20080139577-A1 | Nitroheteroaryl-containing rifamycin derivatives | CUMBRE PHARMACEUTICALS INC. (US) | 2008-06-12 | — | — | US | disclosed |
| WO-2008008480-A2 | NITROHETEROARYL-CONTAINING RIFAMYCIN DERIVATIVES | CUMBRE PHARMACEUTICALS INC. (US) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180265523-A1 | ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS | CLPP, CFTR, ELANE | LMNA 3689/4885RAB9A 1807/4885MAPT 3826/4885 |
| US-20200140460-A1 | ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS | CLPP, CFTR, ELANE | LMNA 3689/4885RAB9A 1807/4885MAPT 3826/4885 |
| US-20080139577-A1 | Nitroheteroaryl-containing rifamycin derivatives | NRDC, FNTB, RIF1 | LMNA 2973/4885RAB9A 973/4885MAPT 2006/4885 |
| US-10570152-B2 | Antibacterial therapeutics and prophylactics | CLPP, CFTR, ELANE | LMNA 3689/4885RAB9A 1807/4885MAPT 3826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.