SCHEMBL24554358

SCHEMBL24554358

C=C/C=C\C=C(/C)Oc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.34
ALDH1A1 P00352 3/20 0.34
MAPT P10636 2/20 0.34
HSP90AA1 P07900 1/20 0.33
GAA P10253 1/20 0.33
TSHR P16473 1/20 0.32
CA4 P22748 1/20 0.32
KMT2A Q03164 1/20 0.32
PAX8 Q06710 1/20 0.32
ATM Q13315 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
SRC P12931 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP19A1 P11511 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22817307 0.86 ELANE (0.37) ELANEALDH1A1MAPTHSP90AA1GAA
SCHEMBL21010421 0.84 ALDH1A1 (0.39) ELANEALDH1A1MAPTHSP90AA1GAA
SCHEMBL12901865 0.84 LMNA (0.46) ALDH1A1MAPTGAATSHRKMT2A
SCHEMBL23733037 0.82 ELANE (0.40) ELANEALDH1A1MAPTHSP90AA1GAA
SCHEMBL20306055 0.82 TDP1 (0.36) ALDH1A1MAPTGAATSHRKMT2A
SCHEMBL19891675 0.81 ELANE (0.36) ELANEALDH1A1MAPTHSP90AA1GAA
SCHEMBL19917249 0.78 TGM2 (0.37) TSHRATML3MBTL1TDP1SRC
SCHEMBL22067559 0.77
SCHEMBL8288104 0.77 ACHE (0.38) ALDH1A1
SCHEMBL24217648 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11639338-B1 Compound producing method, and compound KUREHA CORPORATION (JP) 2023-05-02 US disclosed
US-20230122812-A1 COMPOUND PRODUCING METHOD, AND COMPOUND KUREHA CORPORATION (JP) 2023-04-20 US disclosed
US-20220195350-A1 ANTI-MICROBIAL LIQUID DETERGENT COMPOSITION THE PROCTER AND GAMBLE COMPANY 2022-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11639338-B1 Compound producing method, and compound CA7, CYP3A7, GANC ELANE 3303/4885ALDH1A1 1175/4885MAPT 3597/4885
US-20230122812-A1 COMPOUND PRODUCING METHOD, AND COMPOUND CA7, CYP3A7, GANC ELANE 3303/4885ALDH1A1 1175/4885MAPT 3597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.