SCHEMBL18965889

SCHEMBL18965889

C/N=C\c1ccccc1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALOX15 P16050 2/20 0.41
CASP1 P29466 2/20 0.41
CASP7 P55210 1/20 0.41
GAA P10253 3/20 0.38
RAB9A P51151 2/20 0.38
MAPT P10636 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
NPC1 O15118 1/20 0.37
ALDH1A1 P00352 3/20 0.36
TSHR P16473 4/20 0.35
PIK3CA P42336 1/20 0.35
ADRA2B P18089 1/20 0.34
PTGS1 P23219 1/20 0.34
MAPK1 P28482 1/20 0.33
KDM4E B2RXH2 2/20 0.32
LMNA P02545 1/20 0.32
MEN1 O00255 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21515952 1.00 CYP3A4 (0.41) CYP3A4SMN1; SMN2ALOX15CASP1CASP7
SCHEMBL29213057 0.80 ALOX15 (0.45) CYP3A4SMN1; SMN2ALOX15CASP1CASP7
SCHEMBL866768 0.80 ALOX15 (0.45) CYP3A4SMN1; SMN2ALOX15CASP1CASP7
SCHEMBL866769 0.80 ALOX15 (0.45) CYP3A4SMN1; SMN2ALOX15CASP1CASP7
SCHEMBL4073609 0.76 HPGD (0.47) CYP3A4SMN1; SMN2ALOX15CASP1CASP7
SCHEMBL6088736 0.76 HPGD (0.47) CYP3A4SMN1; SMN2ALOX15CASP1CASP7
SCHEMBL4073613 0.76 HPGD (0.47) CYP3A4SMN1; SMN2ALOX15CASP1CASP7
SCHEMBL6734489 0.76 ALDH1A1 (0.40) CYP3A4SMN1; SMN2ALOX15CASP1CASP7
SCHEMBL12820840 0.76 ALDH1A1 (0.40) CYP3A4SMN1; SMN2ALOX15CASP1CASP7
SCHEMBL6734487 0.76 ALDH1A1 (0.40) CYP3A4SMN1; SMN2ALOX15CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10705274-B2 Optically anisotropic layer and production method therefor, optically anisotropic laminate and production method therefor, optically anisotropic transfer body, polarization plate, and image display device ZEON COPORATION (JP) 2020-07-07 US disclosed
US-10400170-B2 Polymerizable compound, polymerizable composition, polymer, and optically anisotropic product ZEON CORPORATION (JP) 2019-09-03 US disclosed
US-20190113667-A1 OPTICALLY ANISOTROPIC LAYER AND PRODUCTION METHOD THEREFOR, OPTICALLY ANISOTROPIC LAMINATE AND PRODUCTION METHOD THEREFOR, OPTICALLY ANISOTROPIC TRANSFER BODY, POLARIZATION PLATE, AND IMAGE DISPLAY DEVICE ZEON CORPORATION (JP) 2019-04-18 US disclosed
US-20170166815-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC PRODUCT ZEON CORPORATION (JP) 2017-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10400170-B2 Polymerizable compound, polymerizable composition, polymer, and optically anisotropic product CCNA1, CCNA2, CCNO CYP3A4 957/4885SMN1; SMN2 2567/4885ALOX15 273/4885
US-20170166815-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC PRODUCT CCNA1, CCNA2, CCNO CYP3A4 957/4885SMN1; SMN2 2567/4885ALOX15 273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.