SCHEMBL866769

SCHEMBL866769

Nc1ccccc1C=NN=Cc1ccccc1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.45
CYP3A4 P08684 1/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
GAA P10253 2/20 0.43
RAB9A P51151 2/20 0.43
POLB P06746 1/20 0.43
GRIN2D O15399 12/20 0.42
GRIN3B O60391 12/20 0.42
GRIN1 Q05586 12/20 0.42
GRIN2A Q12879 12/20 0.42
GRIN2B Q13224 12/20 0.42
GRIN2C Q14957 12/20 0.42
GRIN3A Q8TCU5 12/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
LMNA P02545 1/20 0.42
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29213057 1.00 ALOX15 (0.45) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL866768 1.00 ALOX15 (0.45) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL6664801 0.89 LMNA (0.62) CYP3A4SMN1; SMN2GAARAB9APOLB
SCHEMBL18965889 0.80 CYP3A4 (0.41) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL4073613 0.80 HPGD (0.47) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL6088736 0.80 HPGD (0.47) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL21515952 0.80 CYP3A4 (0.41) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL4073609 0.80 HPGD (0.47) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL24117294 0.78 ALDH1A1 (0.68) ALOX15CASP1CASP7SMN1; SMN2GAA
SCHEMBL3391624 0.78 CA2 (0.57) ALOX15CYP3A4CASP1CASP7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
WO-2023174773-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2023-09-21 WO disclosed
US-11634544-B2 Photoaligning materials Rolic Technologies AG (CH) 2023-04-25 US disclosed
US-20210340330-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2021-11-04 US disclosed
US-20200223984-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2020-07-16 US disclosed
US-10696795-B2 Photoaligning materials Rolic Technologies AG (CH) 2020-06-30 US disclosed
EP-3374467-B1 COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS ROLIC TECH AG (CH) 2020-04-15 EP disclosed
US-10558089-B2 Photoalignment composition ROLIC AG (CH) 2020-02-11 US disclosed
EP-2222815-B1 PHOTOALIGNMENT COMPOSITION ROLIC TECH AG (CH) 2019-05-29 EP disclosed
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group ROLIC AG (CH) 2019-02-19 US disclosed
US-20120076952-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2012-03-29 US disclosed
EP-2308826-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-13 EP disclosed
EP-2308827-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-13 EP disclosed
EP-2305632-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-06 EP disclosed
EP-2305631-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-06 EP disclosed
US-20100266814-A1 PHOTOALIGNMENT COMPOSITION ROLIC AG (CH) 2010-10-21 US disclosed
EP-2222815-A1 PHOTOALIGNMENT COMPOSITION Rolic Ltd. (CH) 2010-09-01 EP disclosed
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2010-02-25 US disclosed
WO-2009080271-A1 PHOTOALIGNMENT COMPOSITION ROLIC LTD. (CH) 2009-07-02 WO disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group DDC, ALAD, DYNC1LI1 ALOX15 179/4885CYP3A4 4068/4885CASP1 934/4885
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP DDC, ALAD, DYNC1LI1 ALOX15 179/4885CYP3A4 4068/4885CASP1 934/4885
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD ALOX15 1008/4885CYP3A4 4202/4885CASP1 1292/4885
US-20120076952-A1 PHOTOCROSSLINKABLE MATERIALS DDC, PARG, ALAD ALOX15 1008/4885CYP3A4 4202/4885CASP1 1292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.